What are the components of Samter's triad?

Samter's triad, also known as aspirin-exacerbated respiratory disease (AERD), consists of three interrelated conditions: asthma, nasal polyps, and allergy to aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs). This triad occurs in individuals who have asthma and also develop nasal polyps, often leading to recurrent sinus infections.

The presence of asthma in this condition is crucial, as it represents the underlying respiratory issue that can be exacerbated by NSAID exposure. Patients with this triad may experience asthma exacerbations, nasal congestion, and a higher incidence of chronic sinusitis due to the polyps. Recognizing this triad is important for proper management and treatment, particularly in avoiding aspirin and NSAIDs, which can provoke severe respiratory reactions in affected individuals.