What is the serum glucose threshold for failing the glucose loading test at 1 hour?

The glucose loading test, commonly referred to as the oral glucose tolerance test (OGTT), is utilized to assess how well the body processes glucose and is particularly important in diagnosing conditions such as gestational diabetes. The threshold for failing the test is set at a serum glucose level of ≥140 mg/dL measured one hour after administering a glucose solution. This specific cutoff is based on established guidelines that indicate levels above this threshold may suggest impaired glucose metabolism or an increased risk of developing diabetes.

A reading of 140 mg/dL or higher at the one-hour mark indicates that the body isn't responding adequately to the influx of glucose, which can be an early sign of insulin resistance or metabolic dysfunction. This standard is used in clinical practice to flag individuals who may need further testing or monitoring to evaluate their blood glucose control and overall metabolic health.