What is the typical treatment for distributive (septic) shock?

The typical treatment for distributive (septic) shock primarily involves broad-spectrum intravenous antibiotics and vasopressors. In septic shock, the body is experiencing a profound response to infection leading to widespread vasodilation, decreased systemic vascular resistance, and significant hypotension. The administration of broad-spectrum antibiotics is critical for addressing the underlying infection promptly, as delayed treatment can greatly worsen patient outcomes.

Vasopressors are necessary to counteract the effects of peripheral vasodilation and maintain adequate mean arterial pressure, ensuring that perfusion to vital organs is preserved despite the drop in systemic vascular resistance. This combination of antibiotics and vasopressors is a cornerstone of the treatment protocol for septic shock and is recommended by various clinical guidelines.

Other treatment options, such as IV fluids and inotropes, platelet transfusions and IV fluids, or surgical interventions with IV electrolytes, do not encompass the immediate priorities for managing septic shock. While IV fluids can be part of the initial management to correct hypovolemia, the first-line treatments specifically focus on correcting infection and stabilizing hemodynamics through aggressive antibiotic therapy and the use of vasopressors.