What is the usual treatment strategy for severe cases of erythema multiforme?

For severe cases of erythema multiforme, symptomatic therapy is the usual treatment strategy. Erythema multiforme is a condition characterized by target-like lesions on the skin, and while it can be triggered by infections, medications, or other factors, management primarily focuses on alleviating symptoms.

Symptomatic therapy may include the use of analgesics for pain relief, topical corticosteroids to reduce inflammation, and moisturizers or emollients to soothe the skin. In more severe instances, especially if there are mucosal involvement or extensive skin lesions, hospitalization may be required, and the patient may receive supportive care which can include fluids, wound care, and sometimes systemic corticosteroids.

While antiviral medications have a role in treating sores or complications that can arise from specific viral triggers (like herpes simplex virus), they are not the primary treatment for erythema multiforme itself. Antihistamines may relieve itching but do not address the underlying condition. Immediate intubation is not indicated unless there is life-threatening airway compromise, which is rare in cases of erythema multiforme. Thus, the focus remains on symptomatic management to ensure comfort and prevent complications.