Which of the following medications is associated with pill-induced esophagitis?

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Study for the PAEA Emergency Medicine EOR Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Pill-induced esophagitis is a condition characterized by inflammation of the esophagus due to the ingestion of certain medications that can cause direct irritation or ulceration. Nonsteroidal anti-inflammatory drugs (NSAIDs) are particularly notable in this context because they can lead to esophageal injury if they become lodged in the esophagus or if they irritate the esophageal mucosa during ingestion.

NSAIDs can cause a range of gastrointestinal side effects, including erosions and ulcers. When these medications are taken without sufficient water or in a recumbent position, they can remain in contact with the esophageal lining for longer periods of time, increasing the risk of local irritation and inflammation. This makes NSAIDs a well-documented cause of pill-induced esophagitis.

Other medications listed, such as antidepressants, statins, and corticosteroids, can also lead to esophageal problems; however, they are less commonly linked specifically to pill-induced esophagitis compared to NSAIDs. For instance, corticosteroids can cause esophagitis if they are taken without adequate fluid but are usually associated with adverse effects at a different frequency and mechanism. Statins and antidepressants are generally not recognized as common culprits for this particular condition.

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