Which treatment is considered the mainstay for Vibrio cholerae infection?

Fluid replacement is the mainstay treatment for Vibrio cholerae infection, commonly known as cholera. This bacterial infection leads to severe diarrhea and dehydration, which can quickly become life-threatening if not addressed promptly. The primary goal in managing cholera is to restore lost fluids and electrolytes, preventing dehydration and its complications.

Oral rehydration solutions (ORS) are often utilized for mild to moderate cases, while intravenous fluids are necessary for severe dehydration or when oral intake is not possible. The focus on fluid replacement highlights the importance of maintaining hydration and electrolyte balance, rather than targeting the pathogen itself initially.

While other treatments like antibiotics can be beneficial in reducing the duration of diarrhea and the severity of symptoms, they are secondary to fluid replacement. Antivirals, corticosteroids, and antihistamines do not play a role in managing Vibrio cholerae infections, as they are not effective against bacterial infections or not indicated in this context.